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Application of human umbilical cord blood-derived mesenchymal stem cells in disease models.

ABSTRACT: Human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSCs) are regarded as an alternative source of bone marrow-derived mesenchymal stem cells because collection of cord blood is less invasive than that of bone marrow. hUCB-MSCs have recently been studied for evaluation of their potential as a source of cell therapy. In this review, the general characteristics of hUCB-MSCs and their therapeutic effects on various diseases in vitro and in vivo will be discussed.

SUBMITTER: Kim JY 

PROVIDER: S-EPMC3097922 | biostudies-literature | 2010 Apr

REPOSITORIES: biostudies-literature

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Application of human umbilical cord blood-derived mesenchymal stem cells in disease models.

Kim Ju-Yeon JY   Jeon Hong Bae HB   Yang Yoon Sun YS   Oh Wonil W   Chang Jong Wook JW  

World journal of stem cells 20100401 2

Human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSCs) are regarded as an alternative source of bone marrow-derived mesenchymal stem cells because collection of cord blood is less invasive than that of bone marrow. hUCB-MSCs have recently been studied for evaluation of their potential as a source of cell therapy. In this review, the general characteristics of hUCB-MSCs and their therapeutic effects on various diseases in vitro and in vivo will be discussed. ...[more]

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