BSSF: a fingerprint based ultrafast binding site similarity search and function analysis server.

ABSTRACT:

Background

Genome sequencing and post-genomics projects such as structural genomics are extending the frontier of the study of sequence-structure-function relationship of genes and their products. Although many sequence/structure-based methods have been devised with the aim of deciphering this delicate relationship, there still remain large gaps in this fundamental problem, which continuously drives researchers to develop novel methods to extract relevant information from sequences and structures and to infer the functions of newly identified genes by genomics technology.

Results

Here we present an ultrafast method, named BSSF(Binding Site Similarity & Function), which enables researchers to conduct similarity searches in a comprehensive three-dimensional binding site databa

SUBMITTER: Xiong B 

PROVIDER: S-EPMC3098077 | biostudies-literature | 2010 Jan

REPOSITORIES: biostudies-literature