Antifungal 3-hydroxy fatty acids from Lactobacillus plantarum MiLAB 14.

ABSTRACT: We report the identification and chemical characterization of four antifungal substances, 3-(R)-hydroxydecanoic acid, 3-hydroxy-5-cis-dodecenoic acid, 3-(R)-hydroxydodecanoic acid and 3-(R)-hydroxytetradecanoic acid, from Lactobacillus plantarum MiLAB 14. The concentrations of the 3-hydroxy fatty acids in the supernatant followed the bacterial growth. Racemic mixtures of the saturated 3-hydroxy fatty acids showed antifungal activity against different molds and yeasts with MICs between 10 and 100 micrograms ml-1.

SUBMITTER: Sjogren J 

PROVIDER: S-EPMC309954 | biostudies-literature | 2003 Dec

REPOSITORIES: biostudies-literature