Are networks for residual language function and recovery consistent across aphasic patients?

ABSTRACT:

Objectives

If neuroplastic changes in aphasia are consistent across studies, this would imply relatively stereotyped mechanisms of recovery which could guide the design of more efficient noninvasive brain stimulation treatments. To address this question, we performed a meta-analysis of functional neuroimaging studies of chronic aphasia after stroke.

Methods

Functional neuroimaging articles using language tasks in patients with chronic aphasia after stroke (n = 105) and control subjects (n = 129) were collected. Activation likelihood estimation meta-analysis determined areas of consistent activity in each group. Functional homology between areas recruited by aphasic patients and controls was assessed by determining whether they activated under the same experimental conditions

SUBMITTER: Turkeltaub PE 

PROVIDER: S-EPMC3100133 | biostudies-literature | 2011 May

REPOSITORIES: biostudies-literature