Estrogen receptor positive breast cancers and their association with environmental factors.

ABSTRACT:

Background

Epidemiological studies to assess risk factors for breast cancer often do not differentiate between different types of breast cancers. We applied a general linear model to determine whether data from the Surveillance, Epidemiology, and End Results Program on annual county level age-adjusted incidence rates of breast cancer with and without estrogen receptors (ER+ and ER-) were associated with environmental pollutants.

Results

Our final model explained approximately 38% of the variation in the rate of ER+ breast cancer. In contrast, we were only able to explain 14% of the variation in the rate of ER- breast cancer with the same set of environmental variables. Only ER+ breast cancers were positively associated with the EPA's estimated risk of cancer based on toxic a

SUBMITTER: St-Hilaire S 

PROVIDER: S-EPMC3100231 | biostudies-literature | 2011 May

REPOSITORIES: biostudies-literature