Validation of edible taste strips for identifying PROP taste recognition thresholds.

ABSTRACT:

Objectives/hypothesis

The purpose of this study was to validate the use of edible taste strips for measuring taste recognition thresholds for the bitter-tasting compound 6-n-propylthiouracil (PROP).

Study design

Taste recognition thresholds for PROP were obtained by two separate methods. Thresholds were also identified in subjects whose airflow through the nose was blocked. Threshold values were then compared to genotype analysis of the TAS2R38 taste receptor, which is the major determinant for the detection of PROP.

Methods

Edible taste strips were used to examine taste recognition thresholds for PROP. Thresholds were determined by the method of ascending limits and by the method of reversals. Single nucleotide polymorphism analysis of the TAS2R38 gene was used to id

SUBMITTER: Desai H 

PROVIDER: S-EPMC3100437 | biostudies-literature | 2011 Jun

REPOSITORIES: biostudies-literature