Photochemical cleavage of leader peptides.

ABSTRACT: We report a photolabile linker compatible with Fmoc solid phase peptide synthesis and Cu(I)-catalyzed alkyne-azide cycloaddition that allows photochemical cleavage to afford a C-terminal peptide fragment with a native amino terminus.

SUBMITTER: Bindman N 

PROVIDER: S-EPMC3100556 | biostudies-literature | 2010 Dec

REPOSITORIES: biostudies-literature