Sequencing of Neisseria meningitidis penA gene: the key to success in defining penicillin G breakpoints.

ABSTRACT: Testing of susceptibility to penicillin G by E-test and sequencing of an internal fragment of the penA gene were done for 43 meningococcal strains. Those strains for which the MIC was >/=0.094 micro g/ml showed mosaic alleles, so 0.094 micro g/ml is suggested as the penicillin G intermediate breakpoint when E-test is used.

SUBMITTER: Arreaza L 

PROVIDER: S-EPMC310191 | biostudies-literature | 2004 Jan

REPOSITORIES: biostudies-literature