Novel insights into the diversity of catabolic metabolism from ten haloarchaeal genomes.

ABSTRACT:

Background

The extremely halophilic archaea are present worldwide in saline environments and have important biotechnological applications. Ten complete genomes of haloarchaea are now available, providing an opportunity for comparative analysis.

Methodology/principal findings

We report here the comparative analysis of five newly sequenced haloarchaeal genomes with five previously published ones. Whole genome trees based on protein sequences provide strong support for deep relationships between the ten organisms. Using a soft clustering approach, we identified 887 protein clusters present in all halophiles. Of these core clusters, 112 are not found in any other archaea and therefore constitute the haloarchaeal signature. Four of the halophiles were isolated from water, and fou

SUBMITTER: Anderson I 

PROVIDER: S-EPMC3102087 | biostudies-literature | 2011

REPOSITORIES: biostudies-literature