A pilot randomized clinical trial of two medication adherence and drug use interventions for HIV+ crack cocaine users.

ABSTRACT:

Background

Crack cocaine use undermines adherence to highly active antiretroviral therapy (HAART). This pilot randomized clinical trial tested the feasibility and efficacy of 2 interventions based on the Information-Motivation-Behavioral Skill model to improve HAART adherence and reduce crack cocaine problems.

Methods

Participants were 54 adults with crack cocaine use and HIV with <90% HAART adherence. Most participants were African-American (82%) heterosexual (59%), and crack cocaine dependent (92%). Average adherence was 58% in the past 2 weeks. Average viral loads (VL) were detectable (logVL 2.97). The interventions included 6 sessions of Motivational Interviewing plus feedback and skills building (MI+), or Video information plus debriefing (Video+) over 8 weeks. Primary

SUBMITTER: Ingersoll KS 

PROVIDER: S-EPMC3102141 | biostudies-literature | 2011 Jul

REPOSITORIES: biostudies-literature