Ontology highlight
ABSTRACT:
SUBMITTER: Yang YY
PROVIDER: S-EPMC3103785 | biostudies-literature | 2010 Nov
REPOSITORIES: biostudies-literature
Chemistry & biology 20101101 11
The advances in bioorthogonal ligation methods have provided new opportunities for proteomic analysis of newly synthesized proteins, posttranslational modifications, and specific enzyme families using azide/alkyne-functionalized chemical reporters and activity-based probes. Efficient enrichment and elution of azide/alkyne-labeled proteins with selectively cleavable affinity tags are essential for protein identification and quantification applications. Here, we report the synthesis and comparativ ...[more]