Neurobiology of decision making in depressed adolescents: a functional magnetic resonance imaging study.

ABSTRACT:

Objective

Despite evidence that impaired reward- and risk-related behavior during adolescence can have potentially serious short- and long-term consequences, few studies have investigated the impact of depression on reward-related selection in adolescents. This study examined the relationship between reward-related behavior and prefrontal activations in depressed and healthy adolescents during a decision-making task.

Method

A total of 22 adolescents with no personal or family history of psychiatric illness and 22 adolescents with major depressive disorder were administered a monetary, two-option decision-making task, the Wheel of Fortune, using a functional magnetic resonance imaging protocol. The analysis was focused on the selection phase, i.e., the first phase of the deci

SUBMITTER: Shad MU 

PROVIDER: S-EPMC3105351 | biostudies-literature | 2011 Jun

REPOSITORIES: biostudies-literature