Incident hepatitis C virus infection among US HIV-infected men enrolled in clinical trials.

ABSTRACT:

Background

Outbreaks of sexually transmitted hepatitis C virus (HCV) infection have been reported among human immunodeficiency virus (HIV)-infected men who have sex with men in Europe, Australia, and New York. Whether this is occurring across the United States is unknown.

Methods

We determined incidence of HCV infection during 1996-2008 among male participants of the AIDS Clinical Trial Group Longitudinal Linked Randomized Trials cohort, a long-term study of HIV-infected persons randomized into selected US-based clinical trials. We evaluated associations with self-reported injection drug use (IDU), time-varying CD4(+) cell count, and HIV RNA level with use of multivariate Poisson regression. No sexual or non-IDU risk factor data was available.

Results

A total of 1830

SUBMITTER: Taylor LE 

PROVIDER: S-EPMC3106260 | biostudies-literature | 2011 Mar

REPOSITORIES: biostudies-literature