Enantioselective dichlorination of allylic alcohols.

ABSTRACT: The development of an enantioselective allylic alcohol dichlorination catalyzed by dimeric cinchona alkaloid derivatives and employing aryl iododichlorides as chlorine sources is reported. Reaction optimization, exploration of the substrate scope, and a model for stereoinduction are presented.

SUBMITTER: Nicolaou KC 

PROVIDER: S-EPMC3107004 | biostudies-literature | 2011 Jun

REPOSITORIES: biostudies-literature