Axonal transmission in the retina introduces a small dispersion of relative timing in the ganglion cell population response.

ABSTRACT:

Background

Visual stimuli elicit action potentials in tens of different retinal ganglion cells. Each ganglion cell type responds with a different latency to a given stimulus, thus transforming the high-dimensional input into a temporal neural code. The timing of the first spikes between different retinal projection neurons cells may further change along axonal transmission. The purpose of this study is to investigate if intraretinal conduction velocity leads to a synchronization or dispersion of the population signal leaving the eye.

Methodology/principal findings

We 'imaged' the initiation and transmission of light-evoked action potentials along individual axons in the rabbit retina at micron-scale resolution using a high-density multi-transistor array. We measured unimodal

SUBMITTER: Zeck G 

PROVIDER: S-EPMC3107248 | biostudies-literature | 2011

REPOSITORIES: biostudies-literature