Genetic localization of a Drosophila melanogaster resistance gene to a parasitoid wasp and physical mapping of the region.

ABSTRACT: Drosophila melanogaster larvae usually react against eggs of the parasitoid wasp Leptopilina boulardi by surrounding them with a multicellular melanotic capsule. The genetic determinism of this response has been studied previously using susceptible (non-capsule-forming) and resistant (capsule-forming) strains. The results suggest that differences in their encapsulation response involve a single gene, resistance to Leptopilina boulardi (Rlb), with two alleles, the resistant one being dominant. Rlb confers specific protection against Leptopilina boulardi and is thus probably involved in parasitoid recognition. Recent studies have localized this gene on the right arm of the second chromosome and our aim was to precisely determine its genetic and molecular location. Using strains bearing delet

SUBMITTER: Hita MT 

PROVIDER: S-EPMC310767 | biostudies-literature | 1999 May

REPOSITORIES: biostudies-literature