Panel of microsatellite markers for whole-genome scans and radiation hybrid mapping and a mouse family tree.

ABSTRACT: To facilitate whole-genome scan experiments, we selected a panel of 128 microsatellite markers on the basis of spacing and polymorphism in the strains DBA/2, BALB/c, AKR, C57BL/6, C57BL/10, A/J, C3H, 129/J, SJL/J, JF1, and PWB. Many of the primer pairs were redesigned for better performance. The last four strains were not characterized previously using these markers. JF1 and PWB are particularly interesting for intersubspecific crosses offering high polymorphism. We provide allele size data for the markers on these strains and add them to the emerging radiation hybrid framework map, which is not continuous except for chromosome 17 and 13. Information on the interrelationships of strains is useful both because of the importance of polymorphism in designing crosses and the background in asse

SUBMITTER: Schalkwyk LC 

PROVIDER: S-EPMC310811 | biostudies-literature | 1999 Sep

REPOSITORIES: biostudies-literature