A comprehensive approach to clustering of expressed human gene sequence: the sequence tag alignment and consensus knowledge base.

ABSTRACT: The expressed human genome is being sequenced and analyzed by disparate groups producing disparate data. The majority of the identified coding portion is in the form of expressed sequence tags (ESTs). The need to discover exonic representation and expression forms of full-length cDNAs for each human gene is frustrated by the partial and variable quality nature of this data delivery. A highly redundant human EST data set has been processed into integrated and unified expressed transcript indices that consist of hierarchically organized human transcript consensi reflecting gene expression forms and genetic polymorphism within an index class. The expression index and its intermediate outputs include cleaned transcript sequence, expression, and alignment information and a higher fidelity subse

SUBMITTER: Miller RT 

PROVIDER: S-EPMC310831 | biostudies-literature | 1999 Nov

REPOSITORIES: biostudies-literature