Modifiable and fixed factors predicting quality of life in people with colorectal cancer.

ABSTRACT:

Background

People with colorectal cancer have impaired quality of life (QoL). We investigated what factors were most highly associated with it.

Methods

Four hundred and ninety-six people with colorectal cancer completed questionnaires about QoL, functioning, symptoms, co-morbidity, cognitions and personal and social factors. Disease, treatment and co-morbidity data were abstracted from case notes. Multiple linear regression identified modifiable and unmodifiable factors independently predictive of global quality of life (EORTC-QLQ-C30).

Results

Of unmodifiable factors, female sex (P<0.001), more self-reported co-morbidities (P=0.006) and metastases at diagnosis (P=0.036) significantly predicted poorer QoL, but explained little of the variability in the model (R(2)=0.0

SUBMITTER: Gray NM 

PROVIDER: S-EPMC3111166 | biostudies-literature | 2011 May

REPOSITORIES: biostudies-literature