Control region variability of haplogroup C1d and the tempo of the peopling of the Americas.

ABSTRACT:

Background

Among the founding mitochondrial haplogroups involved in the peopling of the Americas, haplogroup C1d has been viewed as problematic because of its phylogeny and because of the estimates of its antiquity, apparently being much younger than other founding haplogroups. Several recent analyses, based on data from the entire mitochondrial genome, have contributed to an advance in the resolution of these problems. The aim of our analysis is to compare the conclusions drawn from the available HVR-I and HVR-II data for haplogroup C1d with the ones based on whole mitochondrial genomes.

Methodology/principal findings

HVR-I and HVR-II sequences defined as belonging to haplogroup C1d by standard criteria were gathered from the literature as well as from population studies ca

SUBMITTER: Figueiro G 

PROVIDER: S-EPMC3113844 | biostudies-literature | 2011

REPOSITORIES: biostudies-literature