Association of maternal genital and reproductive infections with verbal memory and motor deficits in adult schizophrenia.

ABSTRACT: Maternal exposure to genital and reproductive infections has been associated with schizophrenia in previous studies. Impairments in several neuropsychological functions, including verbal memory, working memory, executive function, and fine-motor coordination occur prominently in patients with schizophrenia. The etiologies of these deficits, however, remain largely unknown. We aimed to assess whether prospectively documented maternal exposure to genital/reproductive (G/R) infections was related to these neuropsychological deficits in offspring with schizophrenia and other schizophrenia spectrum disorders. The cases were derived from a population-based birth cohort; all cohort members belonged to a prepaid health plan. Cases were assessed for verbal memory, working memory, executive function

SUBMITTER: Brown AS 

PROVIDER: S-EPMC3114294 | biostudies-literature | 2011 Jul

REPOSITORIES: biostudies-literature