Proteinortho: detection of (co-)orthologs in large-scale analysis.

ABSTRACT:

Background

Orthology analysis is an important part of data analysis in many areas of bioinformatics such as comparative genomics and molecular phylogenetics. The ever-increasing flood of sequence data, and hence the rapidly increasing number of genomes that can be compared simultaneously, calls for efficient software tools as brute-force approaches with quadratic memory requirements become infeasible in practise. The rapid pace at which new data become available, furthermore, makes it desirable to compute genome-wide orthology relations for a given dataset rather than relying on relations listed in databases.

Results

The program Proteinortho described here is a stand-alone tool that is geared towards large datasets and makes use of distributed computing techniques when run o

SUBMITTER: Lechner M 

PROVIDER: S-EPMC3114741 | biostudies-literature | 2011 Apr

REPOSITORIES: biostudies-literature