Interference with work in fibromyalgia: effect of treatment with pregabalin and relation to pain response.

ABSTRACT:

Background

Clinical trials in chronic pain often collect information about interference with work as answers to component questions of commonly used questionnaires but these data are not normally analysed separately.

Methods

We performed a meta-analysis of individual patient data from four large trials of pregabalin for fibromyalgia lasting 8-14 weeks. We analysed data on interference with work, inferred from answers to component questions of Fibromyalgia Impact Questionnaire (FIQ), Short Form 36 Health Survey, Sheehan Disability Scale, and Multidimensional Assessment of Fatigue, including "How many days in the past week did you miss work, including housework, because of fibromyalgia?" from FIQ. Analyses were performed according to randomised treatment group (pregabalin 150-

SUBMITTER: Straube S 

PROVIDER: S-EPMC3118156 | biostudies-literature | 2011 Jun

REPOSITORIES: biostudies-literature