Escherichia coli genome-wide promoter analysis: identification of additional AtoC binding target elements.

ABSTRACT:

Background

Studies on bacterial signal transduction systems have revealed complex networks of functional interactions, where the response regulators play a pivotal role. The AtoSC system of E. coli activates the expression of atoDAEB operon genes, and the subsequent catabolism of short-chain fatty acids, upon acetoacetate induction. Transcriptome and phenotypic analyses suggested that atoSC is also involved in several other cellular activities, although we have recently reported a palindromic repeat within the atoDAEB promoter as the single, cis-regulatory binding site of the AtoC response regulator. In this work, we used a computational approach to explore the presence of yet unidentified AtoC binding sites within other parts of the E. coli genome.

Results

Through the imple

SUBMITTER: Pilalis E 

PROVIDER: S-EPMC3118216 | biostudies-literature | 2011 May

REPOSITORIES: biostudies-literature