Projecting individualized absolute invasive breast cancer risk in Asian and Pacific Islander American women.

ABSTRACT:

Background

The Breast Cancer Risk Assessment Tool (BCRAT) of the National Cancer Institute is widely used for estimating absolute risk of invasive breast cancer. However, the absolute risk estimates for Asian and Pacific Islander American (APA) women are based on data from white women. We developed a model for projecting absolute invasive breast cancer risk in APA women and compared its projections to those from BCRAT.

Methods

Data from 589 women with breast cancer (case patients) and 952 women without breast cancer (control subjects) in the Asian American Breast Cancer Study were used to compute relative and attributable risks based on the age at menarche, number of affected mothers, sisters, and daughters, and number of previous benign biopsies. Absolute risks were obtaine

SUBMITTER: Matsuno RK 

PROVIDER: S-EPMC3119648 | biostudies-literature | 2011 Jun

REPOSITORIES: biostudies-literature