Nutrition, diabetes and tuberculosis in the epidemiological transition.

ABSTRACT:

Background

Diabetes prevalence and body mass index reflect the nutritional profile of populations but have opposing effects on tuberculosis risk. Interactions between diabetes and BMI could help or hinder TB control in growing, aging, urbanizing populations.

Methods and findings

We compiled data describing temporal changes in BMI, diabetes prevalence and population age structure in rural and urban areas for men and women in countries with high (India) and low (Rep. Korea) TB burdens. Using published data on the risks of TB associated with these factors, we calculated expected changes in TB incidence between 1998 and 2008. In India, TB incidence cases would have increased (28% from 1.7 m to 2.1 m) faster than population size (22%) because of adverse effects of aging, urbaniza

SUBMITTER: Dye C 

PROVIDER: S-EPMC3119681 | biostudies-literature | 2011

REPOSITORIES: biostudies-literature