Coffee and acute ischemic stroke onset: the Stroke Onset Study.

ABSTRACT:

Objective

Prior research suggests an acutely elevated risk of myocardial infarction and sudden cardiac death in the hour after coffee intake. However, the risk of ischemic stroke associated with transient exposure to coffee remains unclear. We hypothesized that caffeine intake is associated with a transiently increased risk of ischemic stroke.

Methods

In this multicenter case-crossover study, we interviewed 390 subjects (209 men, 181 women) between January 2001 and November 2006 a median of 3 days after acute ischemic stroke. Each subject's coffee consumption in the hour before stroke symptoms was compared with his or her usual frequency of consumption in the prior year.

Results

Of the 390 subjects, 304 (78%) drank coffee in the prior year, 232 within 24 hours and 35

SUBMITTER: Mostofsky E 

PROVIDER: S-EPMC3120108 | biostudies-literature | 2010 Nov

REPOSITORIES: biostudies-literature