Utility of a panviral microarray for detection of swine respiratory viruses in clinical samples.

ABSTRACT: Several factors have recently converged, elevating the need for highly parallel diagnostic platforms that have the ability to detect many known, novel, and emerging pathogenic agents simultaneously. Panviral DNA microarrays represent the most robust approach for massively parallel viral surveillance and detection. The Virochip is a panviral DNA microarray that is capable of detecting all known viruses, as well as novel viruses related to known viral families, in a single assay and has been used to successfully identify known and novel viral agents in clinical human specimens. However, the usefulness and the sensitivity of the Virochip platform have not been tested on a set of clinical veterinary specimens with the high degree of genetic variance that is frequently observed with swine virus

SUBMITTER: Nicholson TL 

PROVIDER: S-EPMC3122799 | biostudies-literature | 2011 Apr

REPOSITORIES: biostudies-literature