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New Delhi metallo-?-lactamase (NDM-1)-producing Klebsiella pneumoniae: case report and laboratory detection strategies.

ABSTRACT: The spread of antimicrobial resistance among Enterobacteriaceae is a significant clinical threat. We report the first case of an Enterobacteriaceae strain harboring the NDM-1 metallo-?-lactamase in a pediatric patient in the United States. We describe strategies for the detection of this novel resistance mechanism encountered in an isolate of Klebsiella pneumoniae.

SUBMITTER: Mochon AB 

PROVIDER: S-EPMC3122842 | biostudies-literature | 2011 Apr

REPOSITORIES: biostudies-literature

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New Delhi metallo-β-lactamase (NDM-1)-producing Klebsiella pneumoniae: case report and laboratory detection strategies.

Mochon A Brian AB   Garner Omai B OB   Hindler Janet A JA   Krogstad Paul P   Ward Kevin W KW   Lewinski Michael A MA   Rasheed James K JK   Anderson Karen F KF   Limbago Brandi M BM   Humphries Romney M RM  

Journal of clinical microbiology 20110216 4

The spread of antimicrobial resistance among Enterobacteriaceae is a significant clinical threat. We report the first case of an Enterobacteriaceae strain harboring the NDM-1 metallo-β-lactamase in a pediatric patient in the United States. We describe strategies for the detection of this novel resistance mechanism encountered in an isolate of Klebsiella pneumoniae. ...[more]

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