Comparison and correlation of Simple Sequence Repeats distribution in genomes of Brucella species.

ABSTRACT:

Unlabelled

Computational genomics is one of the important tools to understand the distribution of closely related genomes including simple sequence repeats (SSRs) in an organism, which gives valuable information regarding genetic variations. The central objective of the present study was to screen the SSRs distributed in coding and non-coding regions among different human Brucella species which are involved in a range of pathological disorders. Computational analysis of the SSRs in the Brucella indicates few deviations from expected random models. Statistical analysis also reveals that tri-nucleotide SSRs are overrepresented and tetranucleotide SSRs underrepresented in Brucella genomes. From the data, it can be suggested that over expressed tri-nucleotide SSRs in genomic and coding

SUBMITTER: Kiran JA 

PROVIDER: S-EPMC3124796 | biostudies-literature | 2011

REPOSITORIES: biostudies-literature