Palladium(0)-catalyzed arylative dearomatization of phenols.

ABSTRACT: The palladium-catalyzed arylative dearomatization of phenols to yield spirocyclohexadienone products in good to excellent yields has been developed. Preliminary results demonstrate that the formation of the spirocyclic all-carbon quaternary center can be accomplished with high levels of enantiocontrol (up to 91% ee).

SUBMITTER: Rousseaux S 

PROVIDER: S-EPMC3124856 | biostudies-literature | 2011 Jun

REPOSITORIES: biostudies-literature