Prospecting for genes involved in transcriptional regulation of plant defenses, a bioinformatics approach.

ABSTRACT:

Background

In order to comprehend the mechanisms of induced plant defense, knowledge of the biosynthesis and signaling pathways mediated by salicylic acid (SA), jasmonic acid (JA) and ethylene (ET) is essential. Potentially, many transcription factors could be involved in the regulation of these pathways, although finding them is a difficult endeavor. Here we report the use of publicly available Arabidopsis microarray datasets to generate gene co-expression networks.

Results

Using 372 publicly available microarray data sets, a network was constructed in which Arabidopsis genes for known components of SA, JA and ET pathways together with the genes of over 1400 transcription factors were assayed for co-expression. After determining the Pearson Correlation Coefficient cutoff to

SUBMITTER: van Verk MC 

PROVIDER: S-EPMC3125348 | biostudies-literature | 2011 May

REPOSITORIES: biostudies-literature