MiRanalyzer: an update on the detection and analysis of microRNAs in high-throughput sequencing experiments.

ABSTRACT: We present a new version of miRanalyzer, a web server and stand-alone tool for the detection of known and prediction of new microRNAs in high-throughput sequencing experiments. The new version has been notably improved regarding speed, scope and available features. Alignments are now based on the ultrafast short-read aligner Bowtie (granting also colour space support, allowing mismatches and improving speed) and 31 genomes, including 6 plant genomes, can now be analysed (previous version contained only 7). Differences between plant and animal microRNAs have been taken into account for the prediction models and differential expression of both, known and predicted microRNAs, between two conditions can be calculated. Additionally, consensus sequences of predicted mature and precursor microRNA

SUBMITTER: Hackenberg M 

PROVIDER: S-EPMC3125730 | biostudies-literature | 2011 Jul

REPOSITORIES: biostudies-literature