Safety of stenting and endarterectomy by symptomatic status in the Carotid Revascularization Endarterectomy Versus Stenting Trial (CREST).

ABSTRACT:

Background and purpose

The safety of carotid artery stenting (CAS) and carotid endarterectomy (CEA) has varied by symptomatic status in previous trials. The Carotid Revascularization Endarterectomy Versus Stenting Trial (CREST) data were analyzed to determine safety in symptomatic and asymptomatic patients.

Methods

CREST is a randomized trial comparing safety and efficacy of CAS versus CEA in patients with high-grade carotid stenoses. Patients were defined as symptomatic if they had relevant symptoms within 180 days of randomization. The primary end point was stroke, myocardial infarction, or death within the periprocedural period or ipsilateral stroke up to 4 years.

Results

For 1321 symptomatic and 1181 asymptomatic patients, the periprocedural aggregate of stroke, m

SUBMITTER: Silver FL 

PROVIDER: S-EPMC3125963 | biostudies-literature | 2011 Mar

REPOSITORIES: biostudies-literature