High-yield resveratrol production in engineered Escherichia coli.

ABSTRACT: Plant polyphenols have been the subject of several recent scientific investigations since many of the molecules in this class have been found to be highly active in the human body, with a plethora of health-promoting activities against a variety of diseases, including heart disease, diabetes, and cancer, and with even the potential to slow aging. Further development of these potent natural therapeutics hinges on the formation of robust industrial production platforms designed using specifically selected as well as engineered protein sources along with the construction of optimal expression platforms. In this work, we first report the investigation of various stilbene synthases from an array of plant species considering structure-activity relationships, their expression efficiency in microo

SUBMITTER: Lim CG 

PROVIDER: S-EPMC3126431 | biostudies-literature | 2011 May

REPOSITORIES: biostudies-literature