Synthesis of unsymmetrical diarylureas via Pd-catalyzed C-N cross-coupling reactions.

ABSTRACT: A facile synthesis of unsymmetrical N,N'-diarylureas is described. The utilization of the Pd-catalyzed arylation of ureas enables the synthesis of an array of diarylureas in good to excellent yields from benzylurea via a one-pot arylation-deprotection protocol, followed by a second arylation.

SUBMITTER: Breitler S 

PROVIDER: S-EPMC3127456 | biostudies-literature | 2011 Jun

REPOSITORIES: biostudies-literature