Estimating changes in free-living energy intake and its confidence interval.

ABSTRACT:

Background

Free-living energy intake in humans is notoriously difficult to measure but is required to properly assess outpatient weight-control interventions.

Objective

Our objective was to develop a simple methodology that uses longitudinal body weight measurements to estimate changes in energy intake and its 95% CI in individual subjects.

Design

We showed how an energy balance equation with 2 parameters can be derived from any mathematical model of human metabolism. We solved the energy balance equation for changes in free-living energy intake as a function of body weight and its rate of change. We tested the predicted changes in energy intake by using weight-loss data from controlled inpatient feeding studies as well as simulated free-living data from a group of "v

SUBMITTER: Hall KD 

PROVIDER: S-EPMC3127505 | biostudies-literature | 2011 Jul

REPOSITORIES: biostudies-literature