Effects of weight loss on serum vitamin D in postmenopausal women.

ABSTRACT:

Background

Low concentrations of circulating vitamin D are common with obesity and may represent a potential mechanism explaining the elevated risk of certain cancers and cardiovascular outcomes observed in individuals who are overweight or obese.

Objective

The objective of this study was to investigate the effects of 12 mo of weight loss through caloric restriction, exercise intervention, or both on serum 25-hydroxyvitamin D [25(OH)D] concentrations.

Design

Overweight and obese postmenopausal women (n = 439) were randomly assigned to 1 of 4 groups: 1) diet modification (n = 118), 2) exercise (n = 117), 3) diet + exercise (n = 117), or 4) control (n = 87). The diet intervention was a group-based reduced-calorie program with a 10% weight-loss goal. The exercise interve

SUBMITTER: Mason C 

PROVIDER: S-EPMC3127511 | biostudies-literature | 2011 Jul

REPOSITORIES: biostudies-literature