CloudAligner: A fast and full-featured MapReduce based tool for sequence mapping.

ABSTRACT:

Background

Research in genetics has developed rapidly recently due to the aid of next generation sequencing (NGS). However, massively-parallel NGS produces enormous amounts of data, which leads to storage, compatibility, scalability, and performance issues. The Cloud Computing and MapReduce framework, which utilizes hundreds or thousands of shared computers to map sequencing reads quickly and efficiently to reference genome sequences, appears to be a very promising solution for these issues. Consequently, it has been adopted by many organizations recently, and the initial results are very promising. However, since these are only initial steps toward this trend, the developed software does not provide adequate primary functions like bisulfite, pair-end mapping, etc., in on-site soft

SUBMITTER: Nguyen T 

PROVIDER: S-EPMC3127959 | biostudies-literature | 2011 Jun

REPOSITORIES: biostudies-literature