Towards an Age-Phenome Knowledge-base.

ABSTRACT:

Background

Currently, data about age-phenotype associations are not systematically organized and cannot be studied methodically. Searching for scientific articles describing phenotypic changes reported as occurring at a given age is not possible for most ages.

Results

Here we present the Age-Phenome Knowledge-base (APK), in which knowledge about age-related phenotypic patterns and events can be modeled and stored for retrieval. The APK contains evidence connecting specific ages or age groups with phenotypes, such as disease and clinical traits. Using a simple text mining tool developed for this purpose, we extracted instances of age-phenotype associations from journal abstracts related to non-insulin-dependent Diabetes Mellitus. In addition, links between age and phenotype w

SUBMITTER: Geifman N 

PROVIDER: S-EPMC3128036 | biostudies-literature | 2011 Jun

REPOSITORIES: biostudies-literature