Trabecular meshwork gene expression after selective laser trabeculoplasty.

ABSTRACT:

Background

Trabecular meshwork and Schlemm's canal are the tissues appointed to modulate the aqueous humour outflow from the anterior chamber. The impairment of their functions drives to an intraocular pressure increase. The selective laser trabeculoplasty is a laser therapy of the trabecular meshwork able to decrease intraocular pressure. The exact response mechanism to this treatment has not been clearly delineated yet. The herein presented study is aimed at studying the gene expression changes induced in trabecular meshwork cells by selective laser trabeculoplasty (SLT) in order to better understand the mechanisms subtending its efficacy.

Methodology/principal findings

Primary human trabecular meshwork cells cultured in fibroblast medium underwent selective laser trabecul

SUBMITTER: Izzotti A 

PROVIDER: S-EPMC3128580 | biostudies-literature | 2011

REPOSITORIES: biostudies-literature