Clinical practice guidelines for the prevention and treatment of EGFR inhibitor-associated dermatologic toxicities.

ABSTRACT:

Background

Epidermal growth factor receptor inhibitors (EGFRI) produce various dermatologic side effects in the majority of patients, and guidelines are crucial for the prevention and treatment of these untoward events. The purpose of this panel was to develop evidence-based recommendations for EGFRI-associated dermatologic toxicities.

Methods

A multinational, interdisciplinary panel of experts in supportive care in cancer reviewed pertinent studies using established criteria in order to develop first-generation recommendations for EGFRI-associated dermatologic toxicities.

Results

Prophylactic and reactive recommendations for papulopustular (acneiform) rash, hair changes, radiation dermatitis, pruritus, mucositis, xerosis/fissures, and paronychia are presented, as wel

SUBMITTER: Lacouture ME 

PROVIDER: S-EPMC3128700 | biostudies-literature | 2011 Aug

REPOSITORIES: biostudies-literature