Obesity and asthma: an association modified by age of asthma onset.

ABSTRACT:

Background

Studies of asthma phenotypes have identified obesity as a component of a group characterized by a high proportion of subjects with adult-onset asthma. However, whether age of asthma onset modifies the association between obesity and asthma is unknown.

Objectives

We sought to compare the associations between body mass index (BMI) categories with physiological, inflammatory, and clinical parameters across age of asthma onset phenotypes; and to compare the rate of BMI change in relation to asthma duration, by age of onset asthma phenotypes.

Methods

From the Severe Asthma Research Program, we defined age of asthma onset as early (<12 years of age) and late (≥12 years of age). Comparisons of BMI categories were done within age-of-onset groups, and obesity was al

SUBMITTER: Holguin F 

PROVIDER: S-EPMC3128802 | biostudies-literature | 2011 Jun

REPOSITORIES: biostudies-literature