Human bocavirus in patients with respiratory tract infection.

ABSTRACT:

Background

Human bocavirus (HBoV) is a newly identified viral pathogen, and its clinical epidemiology and significance in respiratory infections have not yet been completely elucidated. We investigated the prevalence of HBoV infection and the association between viral (HBoV) load and clinical features of the infection in patients of all age-groups.

Methods

Nasopharyngeal aspirates from patients with symptoms of respiratory infection were tested for presence of HBoV by using real-time polymerase chain reaction. HBoV-positive patients were categorized into low- and high-viral-load groups using 1.0×10(6) copies/mL as the threshold value of viral load.

Results

Detection rate of HBoV was 4.8% (N=93) in a total of 1,926 samples with peak incidence of infection being observe

SUBMITTER: Kim JS 

PROVIDER: S-EPMC3129349 | biostudies-literature | 2011 Jul

REPOSITORIES: biostudies-literature