Total synthesis of bryostatin 9.

ABSTRACT: The total synthesis of bryostatin 9 was accomplished using a uniquely step-economical and convergent Prins-driven macrocyclization strategy. At 25 linear and 42 total steps, this is currently the most concise and convergent synthesis of a potent bryostatin.

SUBMITTER: Wender PA 

PROVIDER: S-EPMC3129979 | biostudies-literature | 2011 Jun

REPOSITORIES: biostudies-literature