Predictors of symptoms are different from predictors of severe exacerbations from asthma in children.

ABSTRACT:

Background

Asthma therapy is typically prescribed and titrated based on patient or parent self-report of symptoms. No longitudinal studies have assessed the relationship between symptoms and severe asthma exacerbations in children. The goal of our study was (1) to assess the association of asthma symptoms with severe asthma exacerbations and (2) to compare predictors of persistent asthma symptoms and predictors of severe asthma exacerbations.

Methods

The Childhood Asthma Management Program was a multicenter clinical trial of 1,041 children randomized to receive budesonide, nedocromil, or placebo (as-needed β-agonist). We conducted a post hoc analysis of diary cards that were completed by subjects on a daily basis to categorize subjects as having persistent vs intermittent sy

SUBMITTER: Wu AC 

PROVIDER: S-EPMC3130529 | biostudies-literature | 2011 Jul

REPOSITORIES: biostudies-literature