Factors associated with the presence of diabetic ketoacidosis at diagnosis of diabetes in children and young adults: a systematic review.

ABSTRACT:

Objective

To identify the factors associated with diabetic ketoacidosis at diagnosis of type 1 diabetes in children and young adults.

Design

Systematic review.

Data sources

PubMed, EMBASE, Web of Science, Scopus, and Cinahl and article reference lists.

Study selection

Cohort studies including unselected groups of children and young adults presenting with new onset type 1 diabetes that distinguished between those who presented in diabetic ketoacidosis and those who did not and included a measurement of either pH or bicarbonate in the definition of diabetic ketoacidosis. There were no restrictions on language of publication.

Results

46 studies involving more than 24,000 children in 31 countries were included. Together they compared 23 different factors. Fa

SUBMITTER: Usher-Smith JA 

PROVIDER: S-EPMC3131115 | biostudies-literature | 2011 Jul

REPOSITORIES: biostudies-literature