Risk factor modification and projections of absolute breast cancer risk.

ABSTRACT:

Background

Although modifiable risk factors have been included in previous models that estimate or project breast cancer risk, there remains a need to estimate the effects of changes in modifiable risk factors on the absolute risk of breast cancer.

Methods

Using data from a case-control study of women in Italy (2569 case patients and 2588 control subjects studied from June 1, 1991, to April 1, 1994) and incidence and mortality data from the Florence Registries, we developed a model to predict the absolute risk of breast cancer that included five non-modifiable risk factors (reproductive characteristics, education, occupational activity, family history, and biopsy history) and three modifiable risk factors (alcohol consumption, leisure physical activity, and body mass index).

SUBMITTER: Petracci E 

PROVIDER: S-EPMC3131219 | biostudies-literature | 2011 Jul

REPOSITORIES: biostudies-literature