SuiteMSA: visual tools for multiple sequence alignment comparison and molecular sequence simulation.

ABSTRACT:

Background

Multiple sequence alignment (MSA) plays a central role in nearly all bioinformatics and molecular evolutionary applications. MSA reconstruction is thus one of the most heavily scrutinized bioinformatics fields. Evaluating the quality of MSA reconstruction is often hindered by the lack of good reference MSAs. The use of sequence evolution simulation can provide such reference MSAs. Furthermore, none of the MSA viewing/editing programs currently available allows the user to make direct comparisons between two or more MSAs. Considering the importance of MSA quality in a wide range of research, it is desirable if MSA assessment can be performed more easily.

Results

We have developed SuiteMSA, a java-based application that provides unique MSA viewers. Users can directl

SUBMITTER: Anderson CL 

PROVIDER: S-EPMC3133551 | biostudies-literature | 2011 May

REPOSITORIES: biostudies-literature