Total synthesis of the cyanolide A aglycon.

ABSTRACT: The synthesis of the potent molluscicide cyanolide A has been achieved in 10 steps without the use of protecting groups. The synthesis features a key Sakurai macrocyclization/dimerization reaction that simultaneously forms both tetrahydropyran rings and the macrocycle of the natural product.

SUBMITTER: Gesinski MR 

PROVIDER: S-EPMC3133735 | biostudies-literature | 2011 Jun

REPOSITORIES: biostudies-literature